{"product_id":"single-arm-phase-ii-survival-trial-design-chapman-hall-crc-biostatistics-series","title":"Single-Arm Phase II Survival Trial Design (Chapman \u0026 Hall\/CRC Biostatistics Series)","description":"\u003cp\u003e\u003cstrong\u003eBook info:\u003c\/strong\u003e Single-Arm Phase II Survival Trial Design (Chapman \u0026amp; Hall\/CRC Biostatistics Series) (Hardcover, 263 pages) – Chapman and Hall\/CRC, 2021. Language: English.\u003c\/p\u003e\n \u003cp\u003eSingle-Arm Phase II Survival Trial Design provides a comprehensive summary to the most commonly- used methods for single-arm phase II trial design with time-to-event endpoints. Single-arm phase II trials are a key component for successfully developing advanced cancer drugs and treatments, particular for target therapy and immunotherapy in which time-to-event endpoints are often the primary endpoints. Most test statistics for single-arm phase II trial design with time-to-event endpoints are not available in commercial software. \u003c\/p\u003e\u003cp\u003eKey Features:\u003c\/p\u003e\u003cul\u003e\u003c\/ul\u003e\u003cp\u003e\u003c\/p\u003e\u003cul\u003e\u003cli\u003eCovers the most frequently used methods for single-arm phase II trial design with time-to-event endpoints in a comprehensive fashion.\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003e\u003c\/p\u003e\u003cul\u003e\u003cli\u003eProvides new material on phase II immunotherapy trial design and phase II trial design with TTP ratio endpoint.\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003e\u003c\/p\u003e\u003cul\u003e\u003cli\u003eIllustrates trial designs by real clinical trial examples \u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003e\u003c\/p\u003e\u003cul\u003e\u003cli\u003eIncludes R code for all methods proposed in the book, enabling straightforward sample size calculation.\u003c\/li\u003e\u003c\/ul\u003e  \n\n                                         Editorial Reviews                   Review   \u003cp\u003e\"I would say it is a great book, great summary of not so common and widely available methods, focusing for a statistical audience with strong statistical skills.\"\u003c\/p\u003e\u003cp\u003eDavid Manteigas, Portugal, ISCB News, June 2022.\u003c\/p\u003e           About the Author   \u003cp\u003eJianrong (John) Wu is a professor in the Division of Cancer Biostatistics, Department of Internal Medicine, University of Kentucky; Biostatistics and Bioinformatics Shared Resource, Markey Cancer Center. Dr. Wu has more than 20 years’ experience of designing and conducting cancer clinical trials at St. Jude Children’s Research Hospital and Markey Cancer Center and has developed many novel statistical methods for designing and monitoring single-arm phase II and randomized phase III trial design with time-to-event endpoints. \u003c\/p\u003e                                           ","brand":"Jianrong Wu","offers":[{"title":"Default Title","offer_id":46070410117354,"sku":"9780367653453","price":175.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0714\/5301\/6298\/files\/61BdNB7EucL._SL1500.jpg?v=1781260784","url":"https:\/\/textbookme.store\/products\/single-arm-phase-ii-survival-trial-design-chapman-hall-crc-biostatistics-series","provider":"TextbookMe","version":"1.0","type":"link"}