{"product_id":"pharmacometrics-the-science-of-quantitative-pharmacology","title":"Pharmacometrics: The Science of Quantitative Pharmacology","description":"\u003cp\u003e\u003cstrong\u003eBook info:\u003c\/strong\u003e Pharmacometrics: The Science of Quantitative Pharmacology (Hardcover, 1232 pages) – Wiley-Interscience, 2007. Language: English.\u003c\/p\u003e\n Pharmacometrics is the science of interpreting and describing pharmacology in a quantitative fashion. The pharmaceutical industry is integrating pharmacometrics into its drug development program, but there is a lack of and need for experienced pharmacometricians since fewer and fewer academic programs exist to train them. Pharmacometrics: The Science of Quantitative Pharmacology lays out the science of pharmacometrics and its application to drug development, evaluation, and patient pharmacotherapy, providing a comprehensive set of tools for the training and development of pharmacometricians. \u003cp\u003eEdited and written by key leaders in the field, this flagship text on pharmacometrics:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eIntegrates theory and practice to let the reader apply principles and concepts.\u003c\/li\u003e\n\u003cli\u003eProvides a comprehensive set of tools for training and developing expertise in the pharmacometric field.\u003c\/li\u003e\n\u003cli\u003eIs unique in including computer code information with the examples.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThis volume is an invaluable resource for all pharmacometricians, statisticians, teachers, graduate and undergraduate students in academia, industry, and regulatory agencies.\u003c\/p\u003e  \n        From the Back Cover   Learn how to perform pharmacometrics to improve drug development success rates\u003cbr\u003e \u003cbr\u003e \u003cp\u003eThis landmark text is the first to pull together and present in one volume the many facets of pharmacometrics. It features an international team of editors and authors who are experts in the field. Readers gain the knowledge base needed to perform pharmacometric analyses, interpret the results, and communicate these results to key decision makers. In particular, the text emphasizes the role of pharmacometrics in drug development, reflecting the field's enormous potential to increase drug development productivity.\u003c\/p\u003e\u003cp\u003eFollowing an introduction that sets forth key landmarks in the history of pharmacometrics, a section on general principles features such topics as essential programming methods and techniques for pharmacometric analysis software validation. Next, the text presents a series of sections designed to enable readers to gain the knowledge needed to grasp pharmacometrics and then apply that knowledge to practical applications:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003ePopulation pharmacokinetic basis of pharmacometrics\u003c\/li\u003e\n\u003cli\u003ePharmacokinetics\/pharmacodynamics relationship, including pharmacogenomics\u003c\/li\u003e\n\u003cli\u003eClinical trial designs\u003c\/li\u003e\n\u003cli\u003ePharmacometric knowledge creation including clinical trial simulation\u003c\/li\u003e\n\u003cli\u003ePharmacometric service and communication\u003c\/li\u003e\n\u003cli\u003eSpecific application examples\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eIn addition to its clear and straightforward presentation of theory and methodology, the text features application examples with codes in NONMEM®, S-PLUS®, WinNonlin®, WinNonmix®, ADAPT®, and MATLAB®. Readers can reproduce the examples themselves and gain a deeper understanding of the many practical benefits of pharmacometrics.\u003c\/p\u003e\u003cp\u003eClinical pharmacologists\/pharmacokineticists and pharmacometricians in drug development and pharmacotherapy, as well as students in clinical pharmacy, pharmaceutical sciences, and clinical pharmacology, should take advantage of this text to gain the training and knowledge needed to excel in pharmacometrics. More experienced pharmacometricians will want to keep the text on hand to address questions and further develop their skills.\u003c\/p\u003e           About the Author   ENE I. ETTE, PhD, is a Fellow of the American Colleges of Clinical Pharmacy and Clinical Pharmacology. He is the President\/CEO of Anoixis Corp. and was formerly the senior director and head of clinical pharmacology at Vertex Pharmaceuticals, Inc. He is also an adjunct professor of applied pharmaceutical sciences at the University of Rhode Island. Dr. Ette was a pioneer pharmacometric staff in the Office of Clinical Pharmacology and Biopharmaceutics at the Food and Drug Administration, where he developed the popular reference Guidance for Industry: Population Pharmacokinetics. From 1989 –2001, he was an FDA Consultant. In recognition of his contributions to clinical pharmacy and clinical pharmacology, Dr. Ette is the recipient of The American College of Clinical Pharmacy's Russell Miller Award. He is also the 2006 recipient of The American College of Clinical Pharmacy's Therapeutic Frontiers Lecture Award. Dr. Ette is chairman of the pharmacometrics panel of The Annals of Pharmacotherapy editorial board. \u003cp\u003ePAUL J. WILLIAMS, PharmD, is a Fellow of the American Colleges of Clinical Pharmacy and Clinical Pharmacology and Professor of Pharmaceutical Sciences and Pharmacy Practice at the Thomas J. Long School of Pharmacy and Health Sciences. Dr. Williams is the Vice President, Strategic Consulting, West Coast Operations in Anoixis Corp. and was formerly a partner at Trials by Design, LLC, a clinical consulting company, and member of the editorial board for The Annals of Pharmacotherapy. Dr. Williams is the 2006 winner of the University of the Pacific Faculty Research Award, the Long's Faculty Fellowship, and Teacher of the Year.\u003c\/p\u003e      ","brand":"Ene I. Ette, Paul J. Williams","offers":[{"title":"Default Title","offer_id":46068535558378,"sku":"9780471677833","price":259.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0714\/5301\/6298\/files\/71gNTN_TXJL._SL1500.jpg?v=1781167663","url":"https:\/\/textbookme.store\/products\/pharmacometrics-the-science-of-quantitative-pharmacology","provider":"TextbookMe","version":"1.0","type":"link"}